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Meta-analyses of Food Sources of Fructose-Containing Sugars and Obesity

NCT02558920 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2019-01-15

No results posted yet for this study

Summary

Sugars have been implicated in the epidemics of overweight and obesity. This view is supported by lower quality evidence from ecological observations, animal models, and select human trials. Higher level evidence from controlled trials and prospective cohort studies has been inconclusive. Whether sugars contribute to weight gain or increases in adiposity independent of their calories and whether important food sources of sugars other than SSBs are associated with a higher risk of overweight and obesity or weight gain remain unclear. To address the uncertainties, the investigators propose to conduct a series of systematic reviews and meta-analyses of the totality of the evidence from controlled trials and prospective cohort studies to distinguish the contribution of fructose-containing sugars and important food sources of sugars (SSBs, fruit, 100% fruit juice, cakes/sweets, yogurt, cereals, etc) from that of energy in the development of overweight and obesity. The findings generated by this proposed knowledge synthesis will help improve the health of consumers through informing evidence-based guidelines and improving health outcomes by educating healthcare providers and patients, stimulating industry innovation, and guiding future research design

Conditions

Interventions

OTHER

Fructose-containing Sugars

An intervention in which calories from food sources of fructose-containing sugars are substituted, added, subtracted, or replaced ad libitum in the diet

Sponsors & Collaborators

  • American Society for Nutrition

    collaborator OTHER

  • The Physicians' Services Incorporated Foundation

    collaborator OTHER

  • Canadian Diabetes Association

    collaborator OTHER

  • John Sievenpiper

    lead OTHER

Principal Investigators

  • John Sievenpiper, MD,PhD,FRCPC · University of Toronto

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-04
Primary Completion
2020-01-31
Completion
2020-09-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02558920 on ClinicalTrials.gov