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Splenda: Effects on Blood Glucose Concentration, Appetite Scores and Subsequent Energy Intake

NCT05810337 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2023-04-12

No results posted yet for this study

Summary

This study investigates the effects of Splenda, an artificial sweetener powder containing sucralose, on post-prandial blood glucose levels, appetite scores and subsequent energy intake.

Conditions

  • Appetitive Behavior
  • Glucose Metabolism Disorders

Interventions

DIETARY_SUPPLEMENT

Splenda drink

4.5g Splenda containing 1% sucralose, 95% maltodextrin, dissolved in 250ml water and consumed with a high carbohydrate breakfast.

DIETARY_SUPPLEMENT

Maltodextrin drink

4.5g maltodextrin dissolved in 250ml water and consumed with a high carbohydrate breakfast.

DIETARY_SUPPLEMENT

High carbohydrate breakfast

Meal consisting of 30g cereal with 100ml skimmed milk, 1.5 slices white toast with 12g margarine, providing 386kcal, 61.4g carbohydrate, 10.4g protein and 10.1g fat.

Sponsors & Collaborators

Principal Investigators

  • Christopher Corpe, Dr. · King's College London

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-18
Primary Completion
2023-02-01
Completion
2023-03-13

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05810337 on ClinicalTrials.gov