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Acute Effects of the Two Alternative Sweeteners D-allulose and Erythritol on Metabolism

NCT04027283 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2020-09-29

No results posted yet for this study

Summary

The aim of this project is to investigate the effect of intragastric (ig) D-allulose on metabolic parameters in general and to investigate the effect of sweet taste receptor blockade on GI hormone responses, glycemic control, gastric emptying (GE) rates and appetite-related sensations to ig administration of erythritol and D-allulose.

Conditions

  • Physiological Satiation Mechanisms

Interventions

DIETARY_SUPPLEMENT

Erythritol

50g erythritol dissolved in 300mL tap water

DIETARY_SUPPLEMENT

Erythritol + lactisole

50g erythritol + lactisole (450ppm) dissolved in 300mL tap water

DIETARY_SUPPLEMENT

D-allulose

25g D-allulose dissolved in 300mL tap water

DIETARY_SUPPLEMENT

D-allulose + lactisole

25g D-allulose + lactisole (450ppm) dissolved in 300mL tap water

DIETARY_SUPPLEMENT

Tap water

300mL tap water

DIETARY_SUPPLEMENT

Tap water + lactisole

300mL tap water + lactisole (450ppm)

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Anne Christin Meyer-Gerspach, PD, PhD · St. Clara Research Ltd.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2020-09-01
Completion
2020-09-01

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04027283 on ClinicalTrials.gov