New research challenges the theory that ketamine's psychedelic effects drive its therapeutic benefits for alcohol use disorder. A study of 96 participants found no link between ketamine's psychoactive experiences and improved abstinence rates. The findings suggest other mechanisms, such as brain network alterations, may explain ketamine's effectiveness in treating addiction.
The Pathways clinical trial into puberty blockers has been paused after the MHRA raised concerns about minimum age limits and unquantified long-term biological risks, with recruitment now suspended pending resolution.
The MHRA has raised new safety concerns about the PATHWAYS clinical trial investigating puberty blockers in young people with gender incongruence, pausing preliminary work until issues are resolved with sponsor King's College London.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07599930 |
Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being |
RECRUITING | NA |
| NCT07586111 |
Effects of Plant Foods on Gastrointestinal and Cardiometabolic Health |
RECRUITING | NA |
| NCT07580781 |
Feasibility of Protocolised Analgosedation in ECMO |
NOT_YET_RECRUITING | NA |
| NCT07563686 |
Measuring Iron Bioavailability From Oral Iron Supplements in Healthy Pre-menopausal Women Using Stable Isotopes |
COMPLETED | NA |
| NCT07560436 |
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction |
RECRUITING | PHASE2 |
| NCT07556692 |
A Study of Home-use Brain Stimulation to Treat Bipolar Depression |
RECRUITING | NA |
| NCT07545096 |
Host Response and Pathogen Genomics in Childhood Respiratory Infection |
NOT_YET_RECRUITING | |
| NCT07541820 |
Tailored Yoga Therapy for Attention-deficit Hyperactivity Disorder |
ACTIVE_NOT_RECRUITING | NA |
| NCT07534917 |
Comparing the Effects of Newer Pacemakers and Their Effects on the Heart and Valve Function in the Short-term. |
NOT_YET_RECRUITING | |
| NCT07533747 |
PRECISE Phenotyping to Guide Therapies for Coronary Microvascular Dysfunction |
NOT_YET_RECRUITING | PHASE3 |
