Meta-analyses of the Effect of Dietary Pulses on Acute Postprandial Metabolic Control

Summary

Dietary pulses (beans, peas, chickpeas, and lentils), more commonly known as "legumes", are generally recognized as healthy components of the diet. Canada's Food Guide encourages consumptions of meat alternatives, such as beans "more often"; and the dietary guidelines for Americans both recommend consumption of 3 cups of legumes per week. However, there remains insufficient information on the usefulness of these foods in protecting heart health. To improve evidence-based guidance for dietary pulse recommendations, the investigators propose to conduct a systematic review of the effect of dietary pulse consumption on after-meal blood sugar levels, appetite, and food intake regulation to help explain their mechanism for improving longterm blood sugar and body weight control. The systematic review process allows the combining of the results from many small studies in order to arrive at a pooled estimate, similar to a weighted average, of the true effect. The investigators will be able to explore whether eating pulses has different effects between men and women, in different age groups and background disease states, and whether or not the effect of pulses depends on the dose and background diet. The findings of this proposed knowledge synthesis will help improve the health of Canadians through informing recommendations for the general public, as well as those at risk of heart disease and diabetes.

Conditions

• Diabetes
• Prediabetes
• Dysglycemia
• Overweight
• Obesity
• Metabolic Syndrome
• Cardiovascular Disease

Interventions

OTHER

Dietary pulses

beans, peas, chickpeas, lentils in whole or flour form

Sponsors & Collaborators

• Pulse Canada

  collaborator OTHER

• Canada Research Chairs Endowment of the Federal Government of Canada

  collaborator OTHER_GOV

• Canadian Institutes of Health Research (CIHR)

  collaborator OTHER_GOV

• John Sievenpiper

  lead OTHER

Principal Investigators

• John L Sievenpiper, MD, PhD · Department of Pathology and Molecular Medicine, McMaster University and Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital

• Russell J de Souza, ScD, RD · Department of Epidemiology and Biostatistics, McMaster University and Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital

• David JA Jenkins, MD, PhD, DSc · Department of Nutritional Sciences and Medicine, University of Toronto and Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital

• Cyril WC Kendall, PhD · Department of Nutritional Sciences, University of Toronto and College of Pharamcy and Nutrition, University of Saskatchewan

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-10-31

Primary Completion

2013-09-30

Completion

2015-12-31

Countries

• Canada

Study Locations