Prediabetes is a metabolic condition with blood glucose levels above normal but below diabetes thresholds, indicating high risk of progression to type 2 diabetes and cardiovascular disease.
A study in Life Metabolism shows that a single post-meal blood biomarker, 1-hour postprandial SPARC, predicts who benefits most from a Mediterranean diet. Lower baseline SPARC-1H levels were linked to greater improvements in insulin resistance and glucose control in a six-month trial.
New research: any cardiometabolic risk factor justifies MASLD screening in overweight adults, and MASLD independently worsens sepsis, bleeding, and other outcomes in hospitalized Crohn's disease patients.
A prototype smart ring tracks multiple metabolic biomarkers in sweat, while Amazon One Medical launches Health Insights for blood biomarker analysis. Pharmacies are also using point-of-care testing to personalize supplement recommendations.
A Tufts trial found high-dose vitamin D cut diabetes risk by 19% in prediabetic adults with AC/CC vitamin D receptor gene variants, but not the AA variant. Published in JAMA Network Open, it supports precision nutrition, but authors urge caution.
A JAMA Network Open study found high-dose vitamin D may reduce progression from prediabetes to type 2 diabetes in people with certain vitamin D receptor genotypes. In participants with ApaI CC or AC alleles, risk fell 19% versus placebo, while no reduction was seen in those with ApaI AA alleles.
Research in the United Kingdom found that preventing type 2 diabetes cut care-related greenhouse gas emissions by about 67%, while well-controlled disease was linked to 21% lower emissions than uncontrolled diabetes.
Recent studies demonstrate that blood-based biomarkers combined with AI can predict dementia risk 25 years early in women, identify liver cancer-prone environments with 93% accuracy, and classify prediabetes risk groups with 90% accuracy.
Health and Human Services Secretary Robert F. Kennedy Jr. announced plans to review the safety of ultra-processed foods, criticizing the GRAS exemption that allows companies to verify ingredient safety without FDA oversight since 1997.
Novo Nordisk sues telehealth companies over compounded weight-loss drugs as employers explore AI-based alternatives to costly GLP-1 medications. About 1 in 8 Americans now take GLP-1 drugs for weight loss or diabetes.
Multiple Indian drugmakers begin selling generic versions of Ozempic and Wegovy following March patent expiration, with prices 50-60% below branded counterparts. The launches signal global pricing shifts as Novo Nordisk faces patent losses across multiple markets.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07762768 |
Effect of CSIR-Developed High-Protein, Low-Glycaemic Index Rice on Glycaemic Response in Individuals With Prediabetes |
NOT_YET_RECRUITING | NA |
| NCT07752225 |
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals |
NOT_YET_RECRUITING | NA |
| NCT07743021 |
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data |
RECRUITING | |
| NCT07714096 |
Cardiometabolic & Cognitive Effects of Peanut Butter in Prediabetes |
NOT_YET_RECRUITING | NA |
| NCT07713394 |
The Effects of Intermittent Fasting on Anthropometric Measurements and Metabolic Parameters in Prediabetic Patients |
COMPLETED | NA |
| NCT07713030 |
Comparative Effects of High-Intensity Interval Training and Continuous Endurance Training Among Prediabetic Patients |
RECRUITING | NA |
| NCT07710898 |
Amelioration of Lipid Profile Through Date Cider-vinegar Along With 5:2 Intermittent Fasting |
COMPLETED | NA |
| NCT07704944 |
Safety and Dose-Response of Bletilla Formosana in Prediabetic Subjects |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07695675 |
Community Dining, Walking, and Glucose in Older Adults |
RECRUITING | NA |
| NCT07690735 |
Investigation of Nutrilite Glucose Health Herbal Drink on Prediabetes Persons |
COMPLETED | NA |
