U of A/ U of M Beans and Peas Health Claim Project

Summary

The purpose of this study is to compare how regularly eating (dried, cooked) beans or peas or rice (control) contained in foods (such as stews or soups) lowers blood lipids, particularly Low Density Lipoprotein cholesterol (LDL-c) in adult men and women with mildly elevated LDL-c . The investigators hypothesize that regularly eating beans or peas will significantly improve LDL-c in these people.

Participants in this study will consume 1 study food item, 5 out of 7 days per week containing beans or peas or rice for a total of 6 weeks. Measuring changes in blood and urinary polyphenol levels may help to verify whether these ingredients play a role in the beneficial actions attributed to regularly eating pulses. It may subsequently assist with the identification of the beneficial bean/pea components. This study will could benefit people who wish to incorporate beans and/or peas into their diet. It may also benefit Canadian pulse growers by enhancing development of food products for human consumption and supporting marketing strategies to increase awareness that a diet rich in pulses can improve LDL-c. This in turn, could enable crop breeders to select for plants that are rich in these compounds.

Conditions

• Hypercholesterolemia

Interventions

DIETARY_SUPPLEMENT

Beans

120g of beans per day for 5 out of 7 days per week will be given to participants for 6 weeks to determine the cholesterol lowering effects of various pulses.

DIETARY_SUPPLEMENT

Control (rice)

110g (3/4 c) of rice per day will be given to the control group to demonstrate the cholesterol lowering effects of the experimental group. This amount of rice equates to a similar volume as 120g of cooked beans or peas.

DIETARY_SUPPLEMENT

Peas

120 grams of peas will be consumed 5 out of 7 days per week

Sponsors & Collaborators

• Alberta Innovates Health Solutions

  collaborator OTHER

• Pulse Canada

  collaborator OTHER

• University of Manitoba

  collaborator OTHER

• University of Alberta

  lead OTHER

Principal Investigators

• Rhonda C Bell, PhD · University of Alberta

• Linda McCargar, PhD · University of Alberta

• Cathy Chan, PhD · university

• Spencer Proctor, PhD · University of Alberta

• Jocelyn Ozga, PhD · University of Alberta

• David Wishart, PhD · University of Alberta

• Carla Taylor, PhD · University of Manitoba

• Peter Zahradka, PhD · University of Manitoba

• Michel Aliani, PhD · University of Manitoba

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

FACTORIAL

Eligibility

Min Age

20 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2013-01-31

Primary Completion

2015-12-31

Completion

2015-12-31

Countries

• Canada

Study Locations