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Canadian Trial of Dietary Carbohydrates in Diabetes

NCT00223574 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 168

Last updated 2005-09-22

No results posted yet for this study

Summary

A long-term low carbohydrate, high monounsaturated fat diet, compared to a high carbohydrate, low glycemic index diet, results in more rapid progression of diabetes; i.e. increased fasting glucose and glycated hemoglobin, reduced beta-cell function and insulin sensitivity and increased free fatty acids. The deleterious effects of a high carbohydrate diet on plasma lipids are only temporary and do not persist beyond 6 months. A long-term high carbohydrate, low glycemic index diet, compared to a high carbohydrate, high glycemic index diet, improves glycemic control and beta-cell function

Conditions

Interventions

DRUG

Control - high carbohydrate, high glycemic index foods

DRUG

high carbohydrate, low glycemic index foods

DRUG

low carbohydrate, high monounsaturate fat foods

Sponsors & Collaborators

  • University of Toronto

    lead OTHER

Principal Investigators

  • Thomas MS Wolever, MD, PhD · University of Toronto/St. Michael's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-01-31
Completion
2004-10-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00223574 on ClinicalTrials.gov