Type 2 diabetes is a chronic metabolic disorder characterized by insulin resistance and progressive beta-cell dysfunction causing hyperglycemia. It is the most common type of diabetes.
A study links sugary drink consumption to anxiety in adolescents, while separate research shows parental substance use patterns strongly influence teen consumption, with authoritative parenting styles offering protective effects.
A review of more than 200 studies linked up to a third of dementia cases to diseases outside the brain. Trials and broader evidence also support multi-domain prevention strategies.
A JAMA Network Open study found high-dose vitamin D may reduce progression from prediabetes to type 2 diabetes in people with certain vitamin D receptor genotypes. In participants with ApaI CC or AC alleles, risk fell 19% versus placebo, while no reduction was seen in those with ApaI AA alleles.
Two studies of older adults with type 2 diabetes linked diabetic retinal disease with higher dementia risk. DME and more severe diabetic retinopathy were associated with higher all-cause and vascular dementia risk, but not consistently with Alzheimer’s disease.
An experimental gut procedure helped a small group of patients maintain up to 80% of weight loss after stopping tirzepatide. A larger trial involving more than 300 people is underway.
GLP-1 drugs used for type 2 diabetes and obesity are seeing rising demand for weight loss as safety concerns also draw attention. A 2025 WHO guideline said long-term safety data remains limited.
Research in the United Kingdom found that preventing type 2 diabetes cut care-related greenhouse gas emissions by about 67%, while well-controlled disease was linked to 21% lower emissions than uncontrolled diabetes.
A Johns Hopkins study found GLP-1 users face increased dementia risk after a decade, possibly due to longer lifespan. A separate JCI review found GLP-1 drugs show neuroprotective signals in preclinical studies but consistent cognitive benefits in humans remain unproven.
A UK trial found continuous glucose monitoring improved HbA1c and time in range for adults with type 2 diabetes using basal insulin. Dexcom is also awaiting a Medicare decision on broader CGM coverage for non-insulin users.
Morphic Medical’s Reset obesity treatment device received NUB status in Germany, allowing hospitals to seek supplementary reimbursement. The company said U.S. FDA study enrollment is continuing after protocol changes to accelerate recruitment.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07602036 |
Type 2 Diabetes and Pregnancy a Single-arm Interventional Study |
NOT_YET_RECRUITING | NA |
| NCT07599852 |
MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients |
NOT_YET_RECRUITING | NA |
| NCT07598773 |
BETA: Study in Prediabetes Type 2 Diabetes |
ENROLLING_BY_INVITATION | |
| NCT07598266 |
Evaluation of a Structured Nutrition Educational Program Among Patients With Type 2 Diabetes |
NOT_YET_RECRUITING | NA |
| NCT07587918 |
Sweet & Sour: Dietary Acid Load in Type 2 Diabetes and Kidney Disease Across Sex and Ethnic Groups |
NOT_YET_RECRUITING | NA |
| NCT07587151 |
Remote Pharmacy Services Plus Continuous Glucose Monitoring in an Underserved Population |
COMPLETED | NA |
| NCT07585630 |
A1Cantus vs. Placebo |
NOT_YET_RECRUITING | PHASE2 |
| NCT07583355 |
Interdisciplinary Counselling in DIAbetes |
RECRUITING | NA |
| NCT07575438 |
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults |
NOT_YET_RECRUITING | PHASE2 |
| NCT07573917 |
Improving Insulin Sensitivity in Patients With Type 2 Diabetes Via Repeated Cold-induced Shivering Thermogenesis |
RECRUITING | NA |
