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Effects of Oral Xylitol on Subsequent Energy Intake

NCT05671965 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2024-08-19

No results posted yet for this study

Summary

The aim of this project is to investigate the effect of xylitol (given as pre-load), compared to sucrose, Ace-K, and water on energy intake during a subsequent ad libitum test meal in healthy participants.

Furthermore, the release of GI hormones, glycemic control, appetite-related sensations, GI tolerance, sweetness and liking in response to the pre-loads will be investigated.

Conditions

  • Energy Intake
  • Gastrointestinal Hormones
  • Glycemic Control
  • Appetite
  • Satiation

Interventions

DIETARY_SUPPLEMENT

Xylitol

33.5g xylitol dissolved in 300mL tap water.

DIETARY_SUPPLEMENT

Sucrose

33.5g sucrose dissolved in 300mL tap water.

DIETARY_SUPPLEMENT

Acesulfame Potassium

0.1675g Ace-K dissolved in 300mL tap water.

DIETARY_SUPPLEMENT

Water

300mL tap water.

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Anne Christin Meyer-Gerspach · St. Clara Research Ltd.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-27
Primary Completion
2024-01-31
Completion
2024-08-15

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05671965 on ClinicalTrials.gov