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Assessment of Reward Responses to Erythritol Using Flavor Preference Learning

NCT05279183 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2022-10-12

No results posted yet for this study

Summary

The aim of this project is to investigate the reward responses to oral erythritol compared to sucrose and sucralose using flavor preference learning in healthy participants. In addition, the release of GI hormones, glycemic control, appetite-related sensations, and emotional state in response to erythritol will be investigated.

Conditions

  • Reward Responses
  • Gastrointestinal Hormones
  • Glycemic Control
  • Appetite
  • Satiation
  • Emotional State

Interventions

DIETARY_SUPPLEMENT

Erythritol

Subject specific dose of erythritol dissolved in 300 mL tap water.

DIETARY_SUPPLEMENT

Sucrose

30 g sucrose dissolved in 300 mL tap water.

DIETARY_SUPPLEMENT

Sucralose

Subject specific dose of sucralose dissolved in 300 mL tap water.

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Anne Christin Meyer-Gerspach, PD, PhD · St. Clara Research Ltd.

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-17
Primary Completion
2022-09-16
Completion
2022-09-16

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05279183 on ClinicalTrials.gov