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Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function

NCT04788680 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2023-11-01

No results posted yet for this study

Summary

The aim of the present study is to determine the effect of non-nutritive sweeteners on intestinal barrier function and inflammatory markers in healthy subjects in comparison to mono- and disaccharides.

Conditions

  • Dietary Habits
  • Endotoxemia

Interventions

OTHER

Dietary intervention 1

Participants receive a beverage with a defined amount of non-nutritive sweetener.

OTHER

Dietary Intervention 2

Participants receive a beverage with a defined amount of non-nutritive sweetener and maltodextrin.

OTHER

Dietary Intervention 3

Participants receive a beverage with a defined amount of monosaccharide.

OTHER

Dietary Intervention 4

Participants receive a beverage with a defined amount of disaccharide.

Sponsors & Collaborators

  • University of Vienna

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04788680 on ClinicalTrials.gov