Fructose and Ethnic Differences Study (FED Study)
NCT02533817 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2016-05-12
Summary
In the UK, people of black West African and Caribbean's tend to have healthier blood cholesterol and blood fat levels, as well as lower incidence of heart disease/heart attack. But rates of heart disease are now rising in young African-American populations with diabetes, for the first time exceeding the rate in their white European-American peers. One possible culprit is the increasing consumption of fructose which can lead to high blood fat levels. Fructose is a natural sugar found in fruits and table sugar but is also used the food industry as an ingredient and sweetener. Because fructose intakes are lower in the UK than in North America we are studying the effect of fructose intake in UK black West African and Caribbean people, to understand if fructose intake is indeed a reason for these ethnic differences.
Conditions
- Healthy
Interventions
- DIETARY_SUPPLEMENT
-
Dietary sugar
This study examined the effect of high intakes of fructose compared to high intakes of glucose in a randomized crossover design. The treatment was in replacement of 20% of the daily caloric requirements for either fructose or glucose for each individual.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Scott V Harding, PhD · King's College London
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-12-31
- Primary Completion
- 2015-07-31
- Completion
- 2015-07-31
More Related Trials
-
High Fructose Diet, the Gut Microbiome, and Metabolic Health
NCT06329544 ·Status: RECRUITING ·Phase: NA
-
The Metabolic Effects of a High Fructose Versus a High Glucose Diet in Overweight Men
NCT01050140 ·Status: COMPLETED ·Phase: NA
-
Acute Effect of Fructose on Lipid Metabolism and Gender Differences
NCT00620360 ·Status: COMPLETED ·Phase: NA
-
Sucrose-sweetened Beverage in African-American and Caucasian Women.
NCT03611972 ·Status: TERMINATED ·Phase: NA
-
Sugar Sweetened Beverages (SSB)- Effects on Metabolism
NCT01733563 ·Status: COMPLETED ·Phase: NA
-
Effects of Dietary Fructose on Glucose and Lipid Metabolism in Healthy Human Subjects
NCT01021969 ·Status: COMPLETED ·Phase: NA
-
Effect of Matrices on Serum Fructose.
NCT05826717 ·Status: COMPLETED ·Phase: NA
-
Effects of Fruit Extracts on Glycaemia: The GLU-FRU Study
NCT02340039 ·Status: COMPLETED ·Phase: NA
-
Genetic-specific Effects of Fructose on Liver Lipogenesis
NCT03783195 ·Status: COMPLETED ·Phase: NA
-
Impacts of Sugar-Sweetened Beverage on Body Weight
NCT04723082 ·Status: COMPLETED
-
Change of Fructose to Fat in South Asians
NCT01562782 ·Status: COMPLETED ·Phase: NA
-
High Fructose Corn Syrup
NCT02018237 ·Status: COMPLETED ·Phase: NA
-
Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks
NCT01165853 ·Status: COMPLETED ·Phase: NA
-
Blood Glucose Control Using African Traditional Fermented Foods
NCT05960019 ·Status: RECRUITING ·Phase: NA
-
Effects of Fructose Restriction on Liver Steatosis
NCT03067428 ·Status: COMPLETED ·Phase: NA
-
Fructose Rich Diet and Endothelial Function
NCT03939130 ·Status: COMPLETED ·Phase: NA
-
Effect of Dietary Fat When Eaten With Fructose Versus Glucose
NCT01061346 ·Status: COMPLETED ·Phase: NA
-
Effects of Sugar Sweetened Beverage on Metabolic Health in Male and Female Adolescents
NCT02058914 ·Status: COMPLETED ·Phase: NA
-
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
NCT01608620 ·Status: UNKNOWN
-
Meta-analyses of Fructose and Cardiometabolic Risk
NCT01363791 ·Status: UNKNOWN
-
Dietary Recommendations for Reducing Free Sugar Intakes
NCT04816955 ·Status: COMPLETED ·Phase: NA
-
Effect of Drinks Containing Fruit Polyphenol Extracts and Fibre on Postprandial Glycaemia. (Glu-MIX)
NCT03572296 ·Status: COMPLETED ·Phase: NA
-
Effects of Dietary Fructose Reduction in Children With Hepatic Steatosis
NCT01188083 ·Status: COMPLETED ·Phase: NA
-
The Impact of the Physiological Response to Sugar on Brain Activity and Behavior
NCT06015490 ·Status: COMPLETED ·Phase: NA
-
Pharmacokinetics and Pharmacodynamics of Fructose
NCT00661947 ·Status: COMPLETED