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Destiffening and Hypotensive Effects of Whole Milk and Full-fat Dairy Products

NCT02397902 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2018-02-01

No results posted yet for this study

Summary

The specific aim of the proposed study is to address the efficacy of conventional full-fat dairy products as part of the normal routine diet for improving vascular function and reducing blood pressure in middle-aged and older adults with elevated blood pressure. The investigators hypothesize that dietary intervention including whole milk and full-fat milk products will induce significant decreases in systolic blood pressure and arterial stiffness. The investigators also test the hypothesis that the reductions in blood pressure will be associated with the corresponding decreases in arterial stiffness and/or increases in endothelial vasodilatory function as well as improvements in arterial baroreflex sensitivity. If our hypotheses are supported by the results, the information could be used as a basis for recommendations for the use of whole milk and full-fat milk products in the secondary prevention of elevated blood pressure and vascular dysfunction.

Conditions

Interventions

DIETARY_SUPPLEMENT

High fat dairy

Add 4 daily servings per day of high fat dairy (yogurt, milk, cheese) for a period of 4 weeks

DIETARY_SUPPLEMENT

Plant-based

Add 4 daily servings of fruit (fruit cup, apple sauce) and/or plant-based milk, remove all dairy for a period for 4 weeks

Sponsors & Collaborators

  • Dairy Management Inc.

    collaborator INDUSTRY

  • University of Texas at Austin

    lead OTHER

Principal Investigators

  • Tanaka Hirofumi, PhD · The University of Texas at Austin

  • Stephen J Roy, MS · The University of Texas at Austin

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2018-01-30
Completion
2018-01-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02397902 on ClinicalTrials.gov