Effect of Brazilian Fruits Peel on Metabolic Regulation and Appetite in Healthy Subjects

Summary

The purpose of the study was to investigate how Brazilian fruits peel affect acute/postprandial glucose and insulin responses, inflammatory markers, appetite control peptides, antioxidative capacity, as well as subjective appetite ratings (VAS-visual analogue scales) in healthy volunteers. We hypothesize that certain Brazilian fruits peel added to a standardized meal will improve postprandial glucose tolerance and other metabolic biomarkers in healthy volunteers, compared with a similar meal without the corresponding plant materials.

Conditions

• Healthy

Interventions

DIETARY_SUPPLEMENT

Control drink

As a control, subjects are asked to consume 300 ml control drinks containing equal amount of total fiber and pectine as Brazilian fruit drink. Following 10 min. beverage consumption, subjects will be given standardized breakfast corresponding to 50 g carbohydrate.

DIETARY_SUPPLEMENT

Brazilian fruit peel flour

In this study, subjects are asked to consume 300 ml beverage drinks contain certain amounts of Brazilian fruit peel flour. Following 10 min. beverage consumption, subjects will be given standardized breakfast corresponding to 50 g carbohydrate.

DIETARY_SUPPLEMENT

Negative control drink

As a negative control, subjects are asked to consume 300 ml control drinks without containing amount of total fiber and pectine as Brazilian fruit drink. Following 10 min. beverage consumption, subjects will be given standardized breakfast corresponding to 50 g carbohydrate.

Sponsors & Collaborators

• University of Campinas, Brazil

  collaborator OTHER

• Lund University

  lead OTHER

Principal Investigators

• Elin Östman, PhD · Lund University

• Glaucia Lima, MSc · Lund University

• Yoghatama Cindya Zanzer, MSc · Lund University

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2014-09-30

Primary Completion

2015-09-30

Completion

2015-09-30

Countries

• Sweden

Study Locations