Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.
NCT07361887 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2026-01-23
Summary
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults. EVs are small particles released by cells that carry proteins, lipids, and genetic material, and play important roles in communication between cells. Participants will consume a single serving of red or white wine, and blood samples will be collected before and after consumption to study changes in the composition and function of EVs. The study will also assess how these EVs affect vascular, immune, and brain-related cells. The results are expected to improve our understanding of how moderate wine intake contributes to cardiovascular and brain health.
Conditions
- Atherosclerosis Cardiovascular Disease
- Obesity
- Metabolic Syndrome
- Metabolic Disorders
- Inflammation
- Neurodegeneration
- Neurodegenerative Disease
- Alzheimer s Disease
Interventions
- DIETARY_SUPPLEMENT
-
White Wine
Chardonnay, 4 mL/kg body weight
- DIETARY_SUPPLEMENT
-
Red Wine
Cabernet Sauvignon, 4 mL/kg body weight
- DIETARY_SUPPLEMENT
-
Water
Still water, 4 mL/kg body weight
Sponsors & Collaborators
-
University of Seville
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 35 Years
- Max Age
- 36 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-11-01
- Primary Completion
- 2025-12-01
- Completion
- 2027-03-31
Countries
- Spain
Study Locations
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