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Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles

NCT06086795 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2026-05-05

No results posted yet for this study

Summary

The goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell profiles in younger vs. older men and women. The study will address the following objectives:

* Objective 1: Determine if daily consumption of egg fractions differentially alter HDL profiles across age groups.
* Objective 2: Determine if daily consumption of egg fractions differentially alter immune cell profiles across age groups.

Participants will be asked to consume egg whites, egg yolks, and whole eggs on a daily basis for 4-weeks each, and avoid eating eggs for a total of 8 weeks at different points in the study. Participants will additionally be provided guidance on following a generally healthy diet, and will be asked to complete surveys about dietary intake and physical activity, as well as provide blood samples throughout the course of the study.

Researchers will compare whether daily consumption of egg whites, egg yolks, and whole eggs differentially alter markers of HDL function and T cell profiles in younger vs. older adults.

Conditions

  • Lipoproteins
  • Inflammatory Response

Interventions

OTHER

Whole eggs

3 large whole eggs per day for 4 weeks

OTHER

Egg yolks

3 large egg equivalent of egg yolks per day for 4 weeks

OTHER

Egg whites

3 large egg equivalent of egg whites per day for 4 weeks

Sponsors & Collaborators

  • American Egg Board

    collaborator OTHER

  • University of Connecticut

    lead OTHER

Principal Investigators

  • Catherine J Andersen, PhD, RDN · University of Connecticut

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-23
Primary Completion
2025-12-29
Completion
2025-12-29

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06086795 on ClinicalTrials.gov