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Dietary Exchanges With Avocado and Mango in Pre-diabetes

NCT05353790 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 82

Last updated 2026-01-15

No results posted yet for this study

Summary

The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals with prediabetes. FMD of the brachial artery, pulse wave velocity (PWV), central blood pressure (cBP), and Optical Coherence Tomography Angiography (OCTA) of the eye will be used for vascular assessments. The research plan will also explore cognitive and kidney function benefits of regular avocado and mango intake using specified cognitive tasks and kidney function biomarkers

Conditions

  • Pre Diabetes
  • Vascular Stiffness
  • Vascular Dilation
  • Cognitive Change
  • Retinal Vascular

Interventions

OTHER

Meals + snacks: control

8 weeks meal plans matched in calories (but not macronutrients or fiber) equivalent to 1 avocado + 1 cup of mango per day

OTHER

Meals + snacks: Avocado mango

8 weeks meal plans provide1 avocado + 1 cup of mango per day

Sponsors & Collaborators

  • Hass Avocado Board

    collaborator OTHER

  • National Mango Board

    collaborator OTHER

  • Clinical Nutrition Research Center, Illinois Institute of Technology

    lead INDUSTRY

Principal Investigators

  • Britt Burton-Freeman, Ph.D · Illinois Institute of Technology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-10-11
Primary Completion
2023-12-06
Completion
2025-12-20

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05353790 on ClinicalTrials.gov