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Effects of Fruit Consumption on Risk Factors of Chronic Disease

NCT01963416 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2013-10-16

No results posted yet for this study

Summary

Acute, randomized, placebo controlled, double blind, postprandial crossover study in male subjects. 4 intervention arms consisting of control, orange juice, whole orange, and processed whole orange to determine the effect of the interventions on the primary measure of flow mediated dilatation (FMD) and additional biomarkers of health. The study will also identify and quantify the main micronutrients and phytochemicals in each of the products and will identify and quantify the main micronutrients and phytochemicals and their metabolites in the subjects' plasma and/or urine. A subset of the study population (n=24) will be invited to participate in an additional arm of the main study which is summarised below.

Conditions

  • Vascular Stiffness

Interventions

DIETARY_SUPPLEMENT

macro- and micro-nutrient matched control (240 ml)

DIETARY_SUPPLEMENT

Orange juice

DIETARY_SUPPLEMENT

whole orange fruit

DIETARY_SUPPLEMENT

Processed whole orange

Sponsors & Collaborators

  • PepsiCo Global R&D

    collaborator INDUSTRY

  • University of Reading

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2012-12-31
Completion
2012-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01963416 on ClinicalTrials.gov