The Dose Effects of Isomaltulose and Sucrose on Glycaemic and Insulinemic Response

Summary

This study will determine the glycaemic and insulinaemic response and sensory profile of the drinks with various ratios sucrose:isomaltulose. The information will be useful for manufacturers of beverages to produce blood glucose friendlier drinks. The information will also be useful for dieticians and clinicians in recommending foods and drinks for people with diabetes. The information will also be useful to the public for making better food choices. The data will also provide insights on how the different ratios of sweeteners may affect glycaemic and insulinaemic indices (GI and II).

Conditions

• Type 2 Diabetes
• Obesity
• Pre Diabetes

Interventions

OTHER

Glucose Solution 1

50g glucose dissolve in 300ml of water

OTHER

Glucose Solution 2

50g glucose dissolve in 300ml of water

OTHER

Glucose Solution 3

50g glucose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 100:0

50g sucrose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 0:100

50g isomaltulose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 50:50

25g sucrose and 25g isomaltulose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 60:40

30g sucrose and 20g isomaltulose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 70:30

35g sucrose and 15g isomaltulose dissolve in 300ml of water

OTHER

Sucrose/Isomaltulose 80:20

40g sucrose and 10g isomaltulose dissolve in 300ml of water

Sponsors & Collaborators

• Singapore Institute of Food and Biotechnology Innovation

  lead OTHER_GOV

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

21 Years

Max Age

60 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-03-01

Primary Completion

2020-10-28

Completion

2020-10-28

Countries

• Singapore

Study Locations