The Role of Secretin on the Energy Homeostasis
NCT04613700 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2020-11-05
Summary
As of last year, new insight into the function of secretin was brought about as rodent studies showed secretin to possess potential body weight-regulating effects. In these studies, secretin was shown to increase non-shivering thermogenesis in brown adipose tissue (BAT), decrease meal size and promote meal discontinuation. The mechanisms behind these regulatory effect of secretin on energy homeostasis are unclear,
Conditions
Interventions
- DRUG
-
Secretin
Native hormone
- OTHER
-
Placebo
Saline
Sponsors & Collaborators
-
Steno Diabetes Center Copenhagen
lead OTHER
Principal Investigators
-
Filip K Knop, Professor, MD · Gentofte Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-03-01
- Primary Completion
- 2020-09-29
- Completion
- 2020-09-29
Countries
- Denmark
Study Locations
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