Role of Adipose Tissue in Pathogenesis of Insulin Resistance
NCT00439491 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2007-02-23
Summary
The aim of the study was to investigate the relationship between insulin resistance and body composition in relation to secterion and expression of adipocytokines. Obese subjects undergo 6 months hypocaloric diet and, before, during and at the end of the diet, plasma samples and subcutaneous adipose tissue samples are obtained for subsequent analysis. In addition, body composition and insulin resistance are measured before and during the diet.
Conditions
Interventions
- BEHAVIORAL
-
Hypocaloric diet
Sponsors & Collaborators
-
Charles University, Czech Republic
lead OTHER
Principal Investigators
-
Vladimir Stich, Ass Prof MD PhD · Third Faculty of Medicine, Charles Uniersity in Prague
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-01-31
- Completion
- 2006-12-31
Countries
- Czechia
Study Locations
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