The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance
NCT00172614 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2006-03-29
Summary
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases. Cytokines secreted by adipose tissue and inflammatory cells play important roles in the pathological conditions. Several novel cytokines were disclosed recently, but their functions have not been well known. Further investigation of these cytokines, resulting in insulin resistance and energy homeostasis, is very important to elucidate the mechanisms and develop new therapeutic strategies.
Conditions
- Metabolic Syndrome X
- Cachexia
- Insulin Resistance
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Jaw-Shiun Tsai, MD · National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-12-31
Countries
- Taiwan
Study Locations
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