Role of Endothelin-1 Modulating Insulin-stimulated Blood Flow and Sympathetic Nervous System Activity in Obesity
NCT05518422 · Status: WITHDRAWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL
Last updated 2024-02-20
Summary
The aim of this project is to determine role for ET-1 in individuals with obesity.
Conditions
- Insulin Resistance
- Autonomic Dysfunction
- Obesity
Interventions
- DRUG
-
Hyperinsulinemic, euglycemic infusion
60 minute infusion
Sponsors & Collaborators
-
University of Missouri-Columbia
lead OTHER
Principal Investigators
-
Jacqueline K Limberg, Ph.D. · University of Missouri-Columbia
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-02-29
- Primary Completion
- 2024-02-29
- Completion
- 2024-02-29
- FDA Drug
- Yes
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