Effects of Macronutrients on Hepatic Lipids, Plasma Triglycerides, and Insulin Sensitivity

NCT00523562 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41

Last updated 2018-06-14

No results posted yet for this study

Summary

The purpose of this study is to assess how the macronutrient composition of the diet effects

* lipid and glucose metabolism
* intrahepatic lipids
* insulin sensitivity

in healthy lean subjects and in subjects with a high metabolic risk (ie overweight and offsprings of patients with type 2 diabetes mellitus).

Conditions

Interventions

OTHER

diet intervention

controlled hypercaloric high fructose, high fat, or high fat/high protein diet

Sponsors & Collaborators

  • University of Lausanne

    lead OTHER

Principal Investigators

  • Luc Tappy, MD · University of Lausanne

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-07-31
Primary Completion
2008-04-30
Completion
2009-01-31

Countries

  • Switzerland

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00523562 on ClinicalTrials.gov