Effects of Macronutrients on Hepatic Lipids, Plasma Triglycerides, and Insulin Sensitivity
NCT00523562 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 41
Last updated 2018-06-14
Summary
The purpose of this study is to assess how the macronutrient composition of the diet effects
* lipid and glucose metabolism
* intrahepatic lipids
* insulin sensitivity
in healthy lean subjects and in subjects with a high metabolic risk (ie overweight and offsprings of patients with type 2 diabetes mellitus).
Conditions
- Metabolic Syndrome X
- Liver Diseases
Interventions
- OTHER
-
diet intervention
controlled hypercaloric high fructose, high fat, or high fat/high protein diet
Sponsors & Collaborators
-
University of Lausanne
lead OTHER
Principal Investigators
-
Luc Tappy, MD · University of Lausanne
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2006-07-31
- Primary Completion
- 2008-04-30
- Completion
- 2009-01-31
Countries
- Switzerland
Study Locations
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