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Anti-Inflammatory Milk Matrix

NCT04216004 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-05-09

No results posted yet for this study

Summary

Obesity is pro-inflammatory, impairs metabolism, and physically limiting. Specifically, muscle in obese persons does not synthesize proteins normally. This further increases metabolic and physical dysfunction. As such, obesity programs should not only focus on weight loss, but muscle metabolic health. Dairy nutrients have anti-inflammatory and anabolic properties, but mostly evaluated in isolation and/or pre-clinical designs. Also, it is unknown if the circulating benefits extend to the muscle. We hypothesize that dairy full-fat milk will improve these obesity characteristics.

Conditions

Interventions

BEHAVIORAL

Controlled-Feeding Intervention

All energy-containing food and beverages will be provided for 1-week as a controlled-feeding study.

DIETARY_SUPPLEMENT

Non-dairy beverage

Isolated amino acid, fatty acid, and monosaccharide beverage matched to the macronutrient content of 8 fl oz whole milk.

OTHER

Full-fat milk

3 daily servings (cup-eq) of full-fat (3.25%) commercial cow's milk.

OTHER

Fat-free milk

3 daily servings (cup-eq) of fat-free (0%) commercial cow's milk.

Sponsors & Collaborators

  • University of Illinois at Urbana-Champaign

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-14
Primary Completion
2023-12-31
Completion
2024-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04216004 on ClinicalTrials.gov