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Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults

NCT03870165 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2020-09-28

No results posted yet for this study

Summary

In a crossover design 10 young healthy adults (20-35 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise participants will ingest either 3.5 oz of Salmon fillet or its constituent macronutrients as isolated amino acids and fat. Repeated blood and breath samples as well as muscle biopsies will be collected to determine whole body amino acid kinetics, muscle amino acid transporters, anabolic signalling and myofibrillar protein synthesis rates during the trials

Conditions

  • Hypertrophy

Interventions

BEHAVIORAL

Resistance exercise

Participants will perform leg press and leg extension immediately prior to ingestion of salmon or isolated mixture

OTHER

Salmon

Participants will ingest salmon immediately after resistance exercise

DIETARY_SUPPLEMENT

Isolated amino acids and fatty acids

Participants will ingest a mixture of isolated amino acids and fatty acids immediately after resistance exercise

Sponsors & Collaborators

  • University of Illinois at Urbana-Champaign

    lead OTHER

Principal Investigators

  • Nicholas A Burd, PhD · University of Illinois at Urbana-Champaign

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2019-11-22
Completion
2019-11-22

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03870165 on ClinicalTrials.gov