Protein Nutrition During Weight Loss

Summary

The purpose of this study is to minimize the loss of lean body mass that occurs during a weight-loss program in obese people by changing the nature of ingested protein and the pattern of protein feeding

Conditions

• Obesity

Interventions

DIETARY_SUPPLEMENT

Pulse casein feeding during energy restriction

Obese subjects are subjected to a 35% energy restriction during 6 weeks and during this period, 25% of energy is given as protein, these proteins being casein. In addition, a pulse protein feeding pattern is used (8% protein in the morning, 80% for lunch, 4% at 1600 h and 8% in the evening).

DIETARY_SUPPLEMENT

Spread casein feeding during energy restriction

Obese subjects are subjected to a 35% energy restriction during 6 weeks and during this period, 25% of energy is given as protein, these proteins being casein. In addition, a spread protein feeding pattern is used (25% of protein at each of the four meals of the day).

DIETARY_SUPPLEMENT

Pulse milk soluble protein feeding during energy restriction

Obese subjects are subjected to a 35% energy restriction during 6 weeks and during this period, 25% of energy is given as protein, these proteins being milk soluble proteins. In addition, a pulse protein feeding pattern is used (8% protein in the morning, 80% for lunch, 4% at 1600 h and 8% in the evening).

DIETARY_SUPPLEMENT

Spread milk soluble protein feeding during energy restriction

Obese subjects are subjected to a 35% energy restriction during 6 weeks and during this period, 25% of energy is given as protein, these proteins being milk soluble proteins. In addition, a spread protein feeding pattern is used (25% of protein at each of the four meals of the day).

Sponsors & Collaborators

• Centre de Recherche en Nutrition Humaine d'Auvergne

  collaborator OTHER_GOV

• ANRS, Emerging Infectious Diseases

  collaborator OTHER_GOV

• Université d'Auvergne

  collaborator OTHER

• Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

  lead OTHER

Principal Investigators

• Yves Boirie, MD, Ph D, Professor · Université d'Auvergne, CHU de Clermont-Ferrand, Institut National de la Recherche Agronomique

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2008-05-31

Primary Completion

2010-07-31

Completion

2010-07-31

Countries

• France

Study Locations