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Impact of Food Combination on Starch Digestion and Gastric Processing

NCT03265392 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2019-06-07

No results posted yet for this study

Summary

The results of our in vitro studies strengthen the hypothesis that the contribution of salivary alpha-amylase to starch digestion has been underrated and that this enzyme can play an important role in this process. As a result, its inhibition could constitute an opportunity to reduce the glycemic response elicited by starch-rich foods. The main goal of this study is to verify whether inhibiting salivary alpha-amylase upon the consumption of starchy foods, can have an impact on the postprandial glycemic response, and/or satiety.

Conditions

  • Glycemic Index
  • Gastric Emptying
  • Appetite

Interventions

OTHER

Bread

Serving of wheat bread providing 50 g of carbohydrates

OTHER

Water

250 mL of water

OTHER

Lemon juice

250 mL of lemon juice

OTHER

Tea

250 mL of tea

OTHER

Peas

20 peas

Sponsors & Collaborators

  • IR4M (Imagerie par Résonance Magnétique Médicale et Multi-Modalités)

    collaborator UNKNOWN

  • Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

    lead OTHER

Principal Investigators

  • Robert Benamouzig, MD, PhD · Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-19
Primary Completion
2018-07-06
Completion
2018-07-06

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03265392 on ClinicalTrials.gov