Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome
NCT03624569 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2025-06-15
Summary
This study is focused on assessing potential health benefits of daily consumption of potatoes, specifically its resistant starch content (i.e. nondigestible carbohydrate), on blood vessel and gut health function in adults with metabolic syndrome. It is expected that the daily consumption of potatoes for two weeks, within a diet that follows the Dietary Guidelines for Americans, will improve blood vessel function in association with decreasing gut permeability ("leaky gut") that results in the absorption of bacterial toxins that reside in the intestine. Outcomes will therefore support dietary recommendations for potatoes to support vascular and gastrointestinal health.
Conditions
- Cardiovascular Diseases
- Endotoxemia
- Endothelial Dysfunction
- Postprandial Hyperglycemia
- Gut Health
Interventions
- OTHER
-
Bagel
A bagel will be consumed daily for 2 weeks.
- OTHER
-
Potato
A potato will be consumed daily for 2 weeks.
Sponsors & Collaborators
-
Alliance for Potato Research and Education
collaborator OTHER -
Ohio State University
lead OTHER
Principal Investigators
-
Richard Bruno, PhD, RD · Ohio State University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-08-15
- Primary Completion
- 2020-07-16
- Completion
- 2020-07-16
Countries
- United States
Study Locations
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