Breakfast Test Products and Acute Satiety Scores

Summary

Rationale: The worldwide prevalence of obesity increases rapidly, and at the moment there are more overweight than underweight people in the world. This is partly caused by increased energy, or food intake. One of the physiological factors regulating the food intake pattern is satiety. Though the regulation of food intake has been studied quite extensively, the underlying mechanisms are not well elucidated yet and still new factors involved in this regulation are being found. Therefore, in this study the investigators aim to develop an in vitro screening tool combined with an in silico model for prediction of satiety, for cost- and time - effective screening of satiating properties of new and existing complex food products and (functional) ingredients, based on actual satiety scores measured. A second aim of the Wholegrain Satiety project is to evaluate satiating properties of different types of wholegrain breads and other oat based products, both for validation purposes and to strengthen the scientific evidence for health benefits of wholegrain products. As part of this study, acute satiety scores after consumption of various breakfast products in well-controlled clinical conditions will be compared with satiety scores obtained in 'at home' test conditions.

Objective: The current study aims to compare the acute satiety effect of carbohydrate breakfast products.

Conditions

• Obesity

Interventions

OTHER

whole wheat bread yeast basis

OTHER

Oatmeal

OTHER

Cheerios

OTHER

whole wheat sourdough bread

OTHER

standard breakfast

Sponsors & Collaborators

• Nederlands Bakkerij Centrum

  collaborator OTHER

• PepsiCo, Inc.

  collaborator INDUSTRY

• TNO

  lead OTHER

Principal Investigators

• Wilrike J Pasman, PhD · TNO

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

50 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-10-31

Primary Completion

2015-12-31

Completion

2016-07-31

Countries

• Netherlands

Study Locations