Effects of Beta-glucan From Barley and Oats on Glucose and Lipid Metabolism, and Satiety

Summary

The interventional study will evaluate the effects of a regularly consumption of barley and oat flakes in crude and roasted form on the glucose and lipid metabolism as well as the postprandial saturation. Moreover, the study will evaluate the effect of a regularly consumption of barley and oat flakes on the glucose and lipid metabolism over a period of three weeks.

All participants will run through each intervention (cross-over design). Inbetween these intervention periods there will be wash-out phases. In total there will be four interventions: crude oat flakes, roasted oat flakes, crude barley flakes and roasted barley flakes. The comparison will be made against white toastbread. The study participants will visit the study centrum before and after each intervention over an entire period of 27 weeks.

Conditions

• Lipid Metabolism
• Glucose Metabolism
• Satiety

Interventions

DIETARY_SUPPLEMENT

Intervention 1

The study participants receive recipes for breakfast for 21 days. The recipes imply 80 g of crude oat flakes per day.

DIETARY_SUPPLEMENT

Intervention 2

The study participants receive recipes for breakfast for 21 days. The recipes imply 80 g of roasted oat flakes per day.

DIETARY_SUPPLEMENT

Intervention 3

The study participants receive recipes for breakfast for 21 days. The recipes imply 80 g of crude barley flakes per day.

DIETARY_SUPPLEMENT

Intervention 4

The study participants receive recipes for breakfast for 21 days. The recipes imply 80 g of roasted barley flakes per day.

DIETARY_SUPPLEMENT

Control

White toastbread (control) (dietary supplement) White toastbread was chosen because of its low fibre content. To achieve the same energy value (kcal) as 80 g cereal flakes the participants have to consume four slices of white toastbread. The study participants receive recipes for breakfast for 21 days. The recipes imply four slices of white toastbread.

Sponsors & Collaborators

• University of Jena

  lead OTHER

Principal Investigators

• Christine Dawczynski, PhD · University of Jena

• Stefan Lorkowski, PhD · University of Jena

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

25 Years

Max Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2018-05-02

Primary Completion

2018-05-31

Completion

2019-07-31

Countries

• Germany

Study Locations