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Evaluation of GCF MMP-1, -8 and Growth Factor Levels in Smokers With Periodontal Health

NCT02014857 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 32

Last updated 2013-12-18

No results posted yet for this study

Summary

Increased levels of cytokines in GCF have been demonstrated in smoker subjects with chronic periodontitis. It is not surprising that increased levels of inflammation associated molecules in GCF has been observed in smokers with periodontitis. However, it is not clear if smoking has an influence on these parameters in periodontally healthy individuals. In the present study, it has been hypothesized that smoking might affect the levels of GCF MMPs and growth factors in young adults with periodontal health.

Conditions

  • Smoking, Healthy Volenteers

Interventions

PROCEDURE

Gingival Crevicular Fluid Sampling

Sponsors & Collaborators

  • Ege University

    lead OTHER

Principal Investigators

  • Gul Atilla, Professor · Ege University School of Dentistry

  • Hatice Oya Turkoglu, Assoc. Professor · Ege University School of Dentistry

  • Harika Atmaca, PhD · Celal Bayar University

Eligibility

Min Age
19 Years
Max Age
27 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2013-09-30
Completion
2013-09-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02014857 on ClinicalTrials.gov