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Study of Gum Tissue Proteins in Smokers vs. Non-smokers After Cleaning

NCT07339670 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-01-14

No results posted yet for this study

Summary

The aim of this study is to evaluate how smoking affects the healing process of the gums after treatment. The researchers will measure the levels of two specific proteins (PLAP-1 and Sclerostin) in the gum fluid of patients with stage II periodontitis. These measurements will be compared between smokers and non-smokers before and after receiving non-surgical periodontal therapy (cleaning and scaling) to see if smoking changes the body's response to treatment.

Conditions

  • Smoking ( Cigarette)
  • Periodontitis Stage II

Interventions

PROCEDURE

Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)

scaling , curettage and root planning

Sponsors & Collaborators

  • Al-Azhar University

    lead OTHER

Principal Investigators

  • Manar Morsi Morsi, MSc · Faculty of Dental Medicine for Girls, Al-Azhar University

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-11
Primary Completion
2025-04-11
Completion
2025-04-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07339670 on ClinicalTrials.gov