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Effects of Smoking on Clinical and Microbiological Response in Individuals With Periodontitis

NCT06383455 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2024-04-25

No results posted yet for this study

Summary

This study aimed to compare the distribution of subgingival periodontal pathogens following non-surgical periodontal therapy in smoking and non-smoking people with periodontitis. The main question it aims to answer is:

\- Does smoking affect the results of non-surgical periodontal treatment on subgingival flora in participants with periodontal disease?

Researchers performed non-surgical periodontal therapy on 48 participants with stage III/IV periodontitis and recorded clinical measurements. They obtained subgingival plaque samples from periodontal pockets at the onset and after four weeks of treatment, determining the level of periodontopathogens using a polymerase chain reaction-based method.

Conditions

  • Periodontitis
  • Smoking Habit
  • Subgingival Plaque

Interventions

PROCEDURE

Non-surgical periodontal therapy

An ultrasonic device (Cavitron Plus, Dentsply®, Duisburg, Germany) and periodontal hand instruments (periodontal curettes; Chicago, IL) were used for non-surgical periodontal treatment. The treatment procedure also included detailed oral hygiene instructions and full-mouth scaling and root planing. Scaling and root planing (SRP) was applied to all four quadrants under local anesthesia in a single appointment. No medication or mouthwash was prescribed to the patients.

Sponsors & Collaborators

  • Trakya University

    lead OTHER

Principal Investigators

  • Ece Açıkgöz-Alparslan · Trakya University

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-15
Primary Completion
2019-02-01
Completion
2019-03-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06383455 on ClinicalTrials.gov