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Effects of Smoking and Vitamin D3 on the Levels of Human Cathelicidin Peptide LL-37

NCT03923218 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2019-04-22

No results posted yet for this study

Summary

The aims of our study were 1) to evaluate levels of gingival crevicular fluid( GCF) human cathelicidin peptide LL-37 and serum vitamin D3 in smoker and non-smoker patients with chronic periodontitis(CP) 2) to determine whether any correlation between GCF LL-37 and vitamin D3 serum levels exist and 3) to asses the correlation between clinical parameters and biochemical markers

Conditions

  • Periodontitis

Interventions

OTHER

LL-37 levels in Gingival crevicular fluid

Collected gingival crevicular fluid

OTHER

Serum Vitamin D3 levels

Collected serum

OTHER

Clinical parameters

Recorded plague index, gingival index, probing depth, clinical attachment level

Sponsors & Collaborators

  • Gazi University

    lead OTHER

Principal Investigators

  • Şeyma BOZKURT DOĞAN, Professor · university

  • Elifcan Kıvrak, PhD · university

Eligibility

Min Age
35 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-12-31
Primary Completion
2012-07-31
Completion
2015-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03923218 on ClinicalTrials.gov