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Apoptotic Changes in Gingiva Caused by Smoking

NCT03631498 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2018-08-16

No results posted yet for this study

Summary

Smoking is a major environmental risk factor associated with common forms of human chronic periodontitis. The aim of the present study was to evaluate apoptotic tissue alterations and tissue destruction in smoker and non-smoker chronic periodontitis patients and healthy individuals. The investigators of the study suggest that smoking decrease tissue quality and increase inflammation level in gingival tissues in both healthy individuals and periodontitis patients. One possible mechanism for this is suggested to be increased apoptosis.

Conditions

  • Smoking
  • Chronic Periodontitis

Sponsors & Collaborators

  • Tokat Gaziosmanpasa University

    lead OTHER

Principal Investigators

  • HATİCE BALCI YÜCE, PhD · Gaziosmanpasa University

Eligibility

Min Age
30 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-10
Primary Completion
2018-01-10
Completion
2018-04-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03631498 on ClinicalTrials.gov