Smoking and Peptidoglycan Recognition Protein-1 and Initial Periodontal Therapy
NCT03915730 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2019-04-16
Summary
A total of 40 patients with CP (20 smokers (S+CP) and 20 nonsmokers (S-CP)) and 40 periodontally healthy subjects (20 smokers (S+PH) and 20 nonsmokers (S-PH)), comprising 80 subjects, were included in this study. Baseline GCF samples were obtained from all subjects and clinical periodontal measurements, including probing depth (PD), clinical attachment level (CAL), plaque index (PI), and gingival index (GI), were recorded. In patients who had received initial periodontal therapy, GCF samples were obtained and all clinical periodontal measurements were recorded again during the 6th-8th weeks. GCF PGRP-1 levels were analyzed by enzyme-linked immunosorbent assay.
Conditions
- Smoking, Cigarette
Interventions
- OTHER
-
Initial periodontal therapy
Scaling and root planing and polishing with specific curettes were performed to patients with CP and oral hygiene education was provided to each patient.
Sponsors & Collaborators
-
Kırıkkale University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 22 Years
- Max Age
- 56 Years
- Sex
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2017-07-31
- Completion
- 2017-11-30
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