Acute Effects of Ultra-processed Versus Unprocessed Foods on Glucocorticoid Secretion in Healthy Individuals
NCT06724692 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2026-03-03
Summary
The investigators aim to understand whether the acute cortisol response to food differs between differently processed foods.
In this monocentric, randomized, cross-over, open-label study, 20 healthy volunteers will receive two differently processed meals of similar caloric content and composition. The study will primarily focus on changes in blood cortisol levels, but other metabolic parameters will also be compared.
Conditions
- Glucocorticoids
- Obesity and Overweight
- Food Effect
Interventions
- OTHER
-
Ultra-processed breakfast
With this intervention, participants will consume ultra-processed foods
- OTHER
-
Low-processed breakfast
With this intervention, participants will consume low-processed foods
Sponsors & Collaborators
-
Eleonora Seelig
lead OTHER
Principal Investigators
-
Eleonora Seelig, PD Dr. med. · Sponsor and principal investigator
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-10-30
- Primary Completion
- 2025-07-04
- Completion
- 2025-07-04
Countries
- Switzerland
Study Locations
More Related Trials
-
Impact of Protein Content of Ultraprocessed Foods on the Regulation of Energy Balance
NCT05337007 ·Status: COMPLETED ·Phase: NA
-
Effects of Ultra Processed Food on Intestinal Energy Harvest
NCT06853288 ·Status: RECRUITING ·Phase: NA
-
Sustained Effect of Food Texture of Ultra-processed Foods on Energy Intake
NCT05561426 ·Status: COMPLETED ·Phase: NA
-
Dietary Interventions to Reduce Ultra-Processed Food Intake
NCT07226336 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning
NCT06165952 ·Status: RECRUITING
-
Dietary Guidelines for Americans-Ultra Processed Study
NCT07252037 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Role of Ultra-processed Foods in Modulating the Effect of Mediterranean Diet
NCT06314932 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Impact of the Eating Rate of Ultra-processed Foods on Dietary Intake Behavior and Metabolic Responses
NCT06113146 ·Status: COMPLETED ·Phase: NA
-
Dissecting the Roles of High-quality Diets and Ultra Processed Foods on Cardiometabolic Health
NCT06749327 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Comparison of Postprandial Inflammation in Lean and Obese Subjects
NCT01446068 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of a Plant-based Ingredient on Generalized Hormonal Responses
NCT02003586 ·Status: COMPLETED ·Phase: NA
-
Food-related Differences in Human Metabolite Profiles
NCT01102049 ·Status: COMPLETED ·Phase: NA
-
Ultra-Processed Foods and Appetite Regulation: Acute Effects Across Body Mass Index Categories
NCT06798220 ·Status: COMPLETED ·Phase: NA
-
Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols
NCT06347094 ·Status: RECRUITING ·Phase: NA
-
Testing Ultraprocessed Food Labels in Chile
NCT06842680 ·Status: COMPLETED ·Phase: NA
-
Impact of Ultra-processed Foods on Cardiometabolic Risk Factors
NCT06538831 ·Status: RECRUITING ·Phase: NA
-
Effects of Breakfast on Cognitive Processes in Children
NCT01063894 ·Status: COMPLETED ·Phase: NA
-
Obesity-related Health Benefits of Apples
NCT03523403 ·Status: COMPLETED ·Phase: NA
-
Effects of Chronic Intake of Processed Foods on Circulating Inflammatory Markers in Healthy Men
NCT02430064 ·Status: COMPLETED ·Phase: NA
-
Analysis of MicroBial Metabolites After Eating Refined Food
NCT04308473 ·Status: COMPLETED ·Phase: NA
-
Elucidation and Monitoring Postprandial Endothelial Function
NCT00766623 ·Status: COMPLETED ·Phase: NA
-
You Are What You Eat: Food As a Risk Factor and a Treatment for Depression
NCT06242665 ·Status: COMPLETED ·Phase: NA
-
Cardiometabolic Risk Factors and Processed Food
NCT06996262 ·Status: COMPLETED
-
A Study Comparing the Health Effects of Two Diets Following UK Dietary Guidance in People Living With Overweight or Obesity
NCT05627570 ·Status: COMPLETED ·Phase: NA
-
Isolating & Exploiting the Mechanisms That Link Breakfast to Human Health - Acute
NCT03866720 ·Status: COMPLETED ·Phase: NA