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The Effect of Medium-chain Fatty Acids on Cardiac Function

NCT06399354 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2025-04-06

No results posted yet for this study

Summary

The effect of an acute intake of medium-chain fatty acids on heart function measured by cardiac magnetic resonance imaging (CMR) will be measured in individuals with heart failure with reduced ejection fraction (HFrEF) and in matched healthy controls with normal heart function. This aim will be investigated in a cross-over study including two visits: acute intake of medium-chain fatty acid or long-chain fatty acid as control. In addition, the effect of acute medium-chain fatty acid compared with long-chain fatty acid intake on whole-body lipid and glucose metabolism will be investigated..

The hypothesis is that acute consumption of medium-chain fatty acid will improve cardiac function in patients with heart failure.

Conditions

Interventions

DIETARY_SUPPLEMENT

acute intake of medium-chain fatty acids or long-chain fatty acids in patients

The intake of an oil comprising of either medium -chain fatty acids or long-chail fatty acids

DIETARY_SUPPLEMENT

Acute intake of medium-chain fatty acids or long-chain fatty acids in healthy individuals

Acute intake of MCT and LCT in healthy individuals in a cross-over design

Sponsors & Collaborators

  • University of Copenhagen

    lead OTHER

Principal Investigators

  • Bente Kiens · University of Copenhagen

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-20
Primary Completion
2025-04-01
Completion
2025-04-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06399354 on ClinicalTrials.gov