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Heart Failure

Disease

Also known as: HF

Disease Profile

Heart failure is a serious clinical syndrome in which the heart cannot pump enough blood and oxygen to meet the body’s needs. It is a chronic condition with episodic decompensation and can cause dyspnea, edema, fatigue, and repeated hospitalizations. Early diagnosis and guideline-directed therapy improve survival and quality of life.

Category
Cardiovascular disease
Prevalence
In the United States, nearly 6.7 million adults aged 20 years or older have heart failure
ICD Codes
  • I50

Related News

Japan's Regenerative Cell Therapy Push Advances With Regulatory Review, Market Growth, and New Patents

Japan's health ministry panel is reviewing two regenerative cell therapies for Parkinson's disease and heart failure, testing the country's push to build a domestic cell-based treatment industry. Japan's cell culture market is projected to reach USD 2.34 billion by 2031, driven by government support and favorable regulatory pathways. Australian firm Cartherics secured a Japanese patent for its iPSC-based immune cell therapies.

CVRx enrolls first patient in BENEFIT-HF heart failure trial

CVRx announced first-patient enrollment in the BENEFIT-HF trial, a 2,500-patient heart failure study across about 150 U.S. and German centers. The trial will evaluate all-cause mortality and heart failure decompensation events through 2032.

Related Clinical Trials

NCT ID Title Status Phase
NCT07613762

High-Flow Nasal Cannula on Exercise Tolerance in Heart Failure Patients Undergoing Cardiac Rehabilitation.

 NOT_YET_RECRUITING NA
NCT07611188

REACTION-VAD Trial: Remote Exercise Training Via Telemedicine in Patients With Long-Term Ventricular Assist Devices

 NOT_YET_RECRUITING NA
NCT07611084

Construction of a Cohort of Elderly Patients With Atrial Fibrillation in Rural China

 RECRUITING
NCT07610174

Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart Valves

 COMPLETED PHASE2
NCT07609381

Clinical Information System Impact on Hospitalized Patients With Chronic Disease

 NOT_YET_RECRUITING
NCT07608393

Validation of the Italian SCHFI v.8 and the CC-SCHFI v.3

 NOT_YET_RECRUITING
NCT07606183

Effects of Different Forms of a Natural Heart Hormone on Blood Pressure and Fluid Balance in Healthy Volunteers

 COMPLETED EARLY_PHASE1
NCT07604727

AV Nodal Ablation With Conduction System Pacing Versus Cardiac Resynchronization for Symptomatic Heart Failure Patients With Atrial Fibrillation

 NOT_YET_RECRUITING NA
NCT07604467

The Role of CD34+ Stem Cells in the Pathogenesis of Takotsubo Syndrome

 RECRUITING
NCT07601867

Effect of Dapagliflozin on Right Ventricular-Pulmonary Artery Coupling After Off-Pump Coronary Atery Bypass Grafting

 NOT_YET_RECRUITING