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Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

NCT06389825 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2024-10-21

No results posted yet for this study

Summary

The investigators will conduct a fully controlled dietary randomized crossover trial (RCT) including 10 adults with HeFH using lipid-lowering medication to investigate the impact of a diet low in red and processed meats and high in plant foods, reflecting Canada's Food Guide, in place of a standard North-American diet on LDL-cholesterol (LDL-C) levels and the plasma metabolome.

Conditions

  • Familial Hypercholesterolemia
  • Nutrition, Healthy
  • Cholesterol, Elevated

Interventions

OTHER

Healthy diet

28-day fully controlled dietary intervention during which participants will receive a diet that reflects the recommendations of Canada's Food Guide.

Sponsors & Collaborators

  • Laval University

    lead OTHER

Principal Investigators

  • Jean-Philippe Drouin-Chartier, PhD · Laval University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-04-01
Primary Completion
2024-06-30
Completion
2024-06-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06389825 on ClinicalTrials.gov