MedTrace Logo

Salt Intake, Hydration Status and Gastrointestinal Discomfort During Fasting

NCT05839860 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2023-09-06

No results posted yet for this study

Summary

This study is part of a hyperhydration project and it has been designed based on a scoping review (Hyperhydration in healthy adults: a scoping review on different methodologies and vehicles utilized) and a previous study (Dietary patterns and gastrointestinal discomfort during Ramadan in a UK Muslim population). The current study aims to examine the impact of different levels of salt intake (6 \& 9 grams) with \[15 milliliters per kilogram of bodyweight (ml/ kg/ bw)\] of water intake during 7 hours of dry fasting compared to a control group (3g salt) under the state of water balance (euhydrated). A previous study and a review by the authors highlighted the potential negative impact of salt and fasting on gastrointestinal (GI) discomfort; hence, the potential negative side effects on gastrointestinal (GI) discomfort during the intervention period will be investigated. By studying a hyperhydration protocol, this research will help the population to reduce dehydration during dry fasting. By doing so, it may improve the quality of life during Ramadan fasting.

Conditions

  • Healthy

Interventions

OTHER

Salt 3 g

Placebo group taking a breakfast meal and 3g salt on tomatoes before fasting for 7 hours

OTHER

Salt 6 g

Intervention group taking a breakfast meal and 6g salt on tomatoes plus 1 L water before fasting for 7 hours

OTHER

Salt 9 g

Intervention group taking a breakfast meal and 9g salt on tomatoes plus 1 L water before fasting for 7 hours

Sponsors & Collaborators

  • Oxford Brookes University

    lead OTHER

Principal Investigators

  • Sangeetha Thondre, PhD · Oxford Brookes University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-14
Primary Completion
2023-05-31
Completion
2023-07-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05839860 on ClinicalTrials.gov