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Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle

NCT05790070 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2023-03-29

No results posted yet for this study

Summary

The purpose of the study is to determine whether there is a synergistic effect via combining both low-load blood flow restriction (BFR) training and betaine supplementation loading (6g/day for 14 days) on skeletal muscle anabolic signaling pathways that is mediated by enhancements in intracellular water. These effects are proposed to be greater than either BFR training or betaine supplementation alone or compared to control conditions (high-load non-occluded and/or placebo supplementation).

Conditions

  • Blood Flow Restriction Training
  • Betaine Supplementation

Interventions

DIETARY_SUPPLEMENT

Betaine

3g/ twice daily (separated by \~12 hours) betaine anhydrous

OTHER

Placebo

3g/ twice daily (separated by \~12 hours) cellulose placebo

Sponsors & Collaborators

  • Baylor University

    lead OTHER

Principal Investigators

  • LesLee Funderburk, PhD · Baylor University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2021-06-30
Completion
2021-07-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05790070 on ClinicalTrials.gov