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Effect of Ketogenic Diet on Muscle Hypertrophy

NCT05897567 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2024-05-10

No results posted yet for this study

Summary

The purpose of this study is to investigate the effects of 4 weeks of carbohydrate deprivation (through a ketogenic diet) on hypertrophy signalling after a single bout of exercise in healthy trained male subjects, and the impact on body composition, muscle strength, and blood parameters.

Conditions

  • Healthy Nutrition

Interventions

OTHER

resistance training

All participants perform a four-day resistance training aimed to stimulate a hypertrophic response.

OTHER

ketogenic diet

Subjects allocated to the ketogenic diet arm (KD group) consume less than 50 g of carbohydrates per day.

OTHER

western diet

Subjects allocated to the western diet arm (WD group) consume a standard diet based on 55% of their daily calories from carbohydrates.

Sponsors & Collaborators

  • University of Padova

    lead OTHER

Principal Investigators

  • Antonio Paoli, MD · University of Padova

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-20
Primary Completion
2025-03-31
Completion
2025-12-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05897567 on ClinicalTrials.gov