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Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy

NCT04371237 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2021-03-10

No results posted yet for this study

Summary

To determine if modalities designed to improve blood flow combined with post-exercise nutrient intake will improve replenishment of muscle glycogen better than nutrient intake alone. A secondary objective is to compare the effectiveness of heat therapy and intermittent pneumatic compression on glycogen replenishment.

Conditions

  • Muscle Recovery
  • Muscle Soreness
  • Glycogen Depletion

Interventions

DEVICE

Compression sleeve

From foot to hip/groin on both legs with only 1 leg connected to pneumatic pump for 1 hour

DEVICE

Heat therapy

Custom leg garment with one leg heated by circulating hot water approx 40 degrees C, the other leg approx 32 degrees C (thermoneutral) for 1 hour

OTHER

Glycogen-depleting exercise session

Prolonged intermittent high intensity running (LIST protocol)

OTHER

Nutrient Intake (beverage)

Post-exercise, all participants will receive a beverage containing 1.0 g/kg carbohydrate and 0.3 g/kg protein from the mixture of Gatorade Recover Protein Shake and Gatorade Thirst Quencher

PROCEDURE

Skeletal muscle biopsy

Vastus lateralis muscle in the lower thigh will be obtained by the percutaneous needle technique

Sponsors & Collaborators

  • PepsiCo Global R&D

    lead INDUSTRY

Principal Investigators

  • Bruno Roseguini, PhD · Purdue University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-19
Primary Completion
2019-12-21
Completion
2019-12-21

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04371237 on ClinicalTrials.gov