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Fasting and Exercise-induced Changes in Human Skeletal Muscle

NCT03811717 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2019-05-30

No results posted yet for this study

Summary

This study examines the impact of increasing energetic stress during an 8-hour fast on metabolic pathways in human skeletal muscle. Specifically, participants will undergo two 8-hour fasting sessions in a randomized crossover fashion, with the addition of low-intensity arm exercise in one of the sessions. Changes in metabolic pathways will be examined in resting (leg) muscle before, during, and after the fast.

Conditions

  • Skeletal Muscle Energetics

Interventions

OTHER

FAST+EX

Participants will perform 2-hours of low-intensity arm exercise (8 x 15 min bouts of arm ergometer exercise separated by 10 min of rest) during an 8-hour fast.

OTHER

FAST

Participants will complete an 8-hour fast.

Sponsors & Collaborators

  • University of Waterloo

    collaborator OTHER

  • Queen's University

    lead OTHER

Principal Investigators

  • Brendon J. Gurd, PhD · Queen's University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-14
Primary Completion
2019-04-30
Completion
2019-04-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03811717 on ClinicalTrials.gov