Exercise and Branched Chain Amino Acids (BCAA)Requirements in Older Men
NCT01931722 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2016-01-12
Summary
Likely, branched chain amino acid (BCAA) requirements are increased in older strength-trained (ST) individuals. If so, supplementation in this group will maximize muscle protein synthesis (MPS) and minimize loss of muscle with age (sarcopenia).
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Branched chain amino acid
seven graded intakes of a BCAA (branched chain amino acid) mixture from 50 to 350 mg.kg-1.d-1 will be used to measure BCAA requirement
- BEHAVIORAL
-
Strength training
Strength training will include a split-training program using all major muscle groups of the body on a three day "on", one day "off" protocol. Muscle areas targeted on each training day will be as follows: Day1: chest, shoulder, triceps; Day2: back, biceps; Day3: legs and calfs; Day4: will be a rest day. On Day5: this cycle will begin again. A combination of free weights and machines will be used for each training day. Progressive overload protocol will be applied where the load used by every participant will be adjusted bi-weekly based on their 70% of 1 repetition maximum (maximum weight that can be lifted only one time). Instruction will be provided for all exercises and professional trainers will oversee all training sessions.
Sponsors & Collaborators
-
University of Western Ontario, Canada
lead OTHER
Principal Investigators
-
Peter Lemon, PhD · The University of Western Ontario
-
Arash Bandegan, MSc. · The University of Western Ontario
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 55 Years
- Max Age
- 65 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2016-12-31
- Completion
- 2016-12-31
Countries
- Canada
Study Locations
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