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Cardiovascular Risk Prevention With a Mediterranean Dietary Pattern Reduced in Saturated Fat

NCT05778656 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 157

Last updated 2026-01-02

No results posted yet for this study

Summary

The Cardiovascular Risk Prevention With a Mediterranean Dietary Pattern Reduced in Saturated Fat (CADIMED) study is a randomized, controlled intervention trial aiming to develop a dietary intervention that promotes saturated fat (SFA) reduction through eliminating red and processed meat consumption and to evaluate its impact on lipid and cardiovascular disease (CVD) risk biomarkers.

The main research question is:

\* Does lowering SFA intake from specific foods (e.g., red and processed meat) modify cardiovascular risk factors in a Mediterranean dietary pattern context?

The aim is to compare, in a sample of 156 adult subjects (\>18 years) with dyslipidemia, the effect of an intervention that promotes the elimination of red and processed meat intake vs. the control group that will follow the usual health advice for CVD prevention. Changes in CVD risk biomarkers, blood metabolomics and the microbiome will be investigated after 8 weeks of intervention.

Conditions

  • LDL Cholesterol

Interventions

BEHAVIORAL

Cardiovascular Risk Prevention with a Mediterranean Dietary Pattern Reduced in Saturated Fat

Eight-week behavioral intervention consisting of a Mediterranean dietary pattern with elimination of red and processed meat

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • University of Copenhagen

    collaborator OTHER

  • Norwegian Veterinary Institute

    collaborator UNKNOWN

  • Harvard University

    collaborator OTHER

  • University Hospital Virgen de las Nieves

    collaborator OTHER

  • Universidad de Granada

    lead OTHER

Principal Investigators

  • Carmen Piernas, PhD · Universidad de Granada

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-19
Primary Completion
2025-08-06
Completion
2025-08-06

Countries

  • Spain

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05778656 on ClinicalTrials.gov