Also known as: Harvard
Penn joined 35 universities in an amicus brief supporting Harvard’s lawsuit against a $2 billion federal research funding freeze. The brief warns that such cuts endanger basic research and innovation, as Penn itself faces over $400 million in recent funding freezes and cuts.
Two new studies clarify how Epstein-Barr virus may trigger multiple sclerosis: one shows a doubled CD4+ T cell response in untreated patients, while another reveals EBV-activated B cells cause brain inflammation in mice. Insights point to potential therapies targeting EBV-specific immune activity.
Portal Biotechnologies closes $9M funding round to expand cell engineering platform for drug discovery and cell therapy. Navikenz raises $7.5M seed round to scale AI transformation services focused on life sciences and pharmaceuticals.
Congress rejected the administration’s deepest proposed science cuts, increasing NIH funding by about $415 million to $48.7 billion. NASA and NSF also saw far smaller reductions than proposed.
The FDA has issued draft guidance creating a "Plausible Mechanism Framework" to accelerate approval of individualized therapies for ultra-rare diseases where traditional clinical trials are not feasible. The guidance focuses on gene editing and RNA-based treatments targeting specific genetic abnormalities.
Thousands of research positions have been terminated or frozen at federal agencies following deep cuts to U.S. science funding by the Trump administration, affecting work from aging studies to global food security.
The World Health Organization published blueprints for urgently needed antibiotics targeting drug-resistant infections, while CARB-X awarded $1.2 million for novel antibiotic research and the FDA issued guidance on antibiotic duration limits in livestock.
Artificial intelligence is revolutionizing rare disease diagnosis, cutting diagnostic timelines from years to weeks. Rare Disease Day on February 28 highlights challenges faced by over 300 million people worldwide living with more than 7,000 distinct rare conditions.
Researchers at Stanford and Harvard are developing nasal spray vaccines offering broad protection against respiratory infections, with early animal and phase 1 human trials showing safety and potential efficacy.
The controversy over direct-to-consumer prescription drug advertising has gained renewed attention from the Trump administration and legislators, with spending reaching $9 billion in 2024 and debate centering on whether such ads benefit or harm consumers.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07759466 |
Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease |
COMPLETED | |
| NCT07666672 |
Digital Coach to Support Exposure Therapy Homework for Anxious Youth |
NOT_YET_RECRUITING | NA |
| NCT07601685 |
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) |
COMPLETED | |
| NCT07592052 |
Circadian Clock Proteins in Gingival Crevicular Fluid of Individuals With and Without Circadian Rhythm Disruption |
NOT_YET_RECRUITING | |
| NCT07394465 |
First Tones: Artistic Communal Practices for 4 and 5 Year Old Children |
COMPLETED | NA |
| NCT07381049 |
Effect of Cash Benefits on Health Care Spending |
ACTIVE_NOT_RECRUITING | NA |
| NCT07316647 |
Using Conversational AI to Teach Growth Mindset Skills to Youths in India |
COMPLETED | NA |
| NCT07286955 |
Life Skills Training for Soldiers Arriving at Their First Duty Location |
RECRUITING | NA |
| NCT07218107 |
Neurostimulation Exosuit Augmented Training (NEAT) in the Clinic |
COMPLETED | NA |
| NCT07212608 |
Personalized Post-Stroke Gait Rehabilitation Interventions |
COMPLETED | NA |
